Abstract

In our earlier article [1], we had shown the application of Hammett equation of finding the site of attack. The application is based on the relative position of substituent on the aromatic ring from the center of the reaction. We had shown why we have to use σ_m value for σ_p and σ_p value for σ_m value, when we use Hammett’s plot. In the present article we have demonstrated the use of the Taft equation for finding the site of attack. Here too, similar necessity arises. Often occasion arises in research, related to oxidation of aliphatic amines, where there is more than one site of attack, and we have to find the right one. One of the sites may be the N-H bond of the functional group; others being the α-C-H bond and the lone pair of electrons of the nitrogen atom. In such a circumstance, the Taft equation plays a deciding role in location of the site of attack. This equation is apparently simple but requires judicious application. It is in the fitness of this aspect, an attempt is made to make the application more understandable and student friendly. Also we feel that it should be essential part of Physical Organic Chemistry Graduate Curriculum.