ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
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Abstract

pH-Metric Studies of  Mixed Ligand Complexes of Zn(II) With Famotidine and Peptides

Salhah D. Al-Qahtani

DOI : http://dx.doi.org/10.13005/ojc/330447


Abstract:

Solution equilibria of the ternary complexes of Zn(II) with famotidine‎ (FAM) as primary ligand and peptides (L) as secondary ligands have been studied pH-metrically under the experimental conditions (25°C and ionic strength I = 0.10 mol/L NaNO3).  Ternary complexes are formed by a simultaneous mechanism. The concentration distribution of the complexes in solution was evaluated as a function of pH. The values of Δ log K values for the ternary complexes have been evaluated and discussed

Keywords:

Famotidine; Peptides; Stability constants; Potentiometric titration

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