Abstract

Ahlam Jameel Abdulghani and Saja Khalil Mohuee

DOI : http://dx.doi.org/10.13005/ojc/330327

Gold nanoparticles AuNPs were synthesized in aqueous solutions at different conditions  via the reduction of sodium tetrachloroaurate (III) (NaAuCl₄) by the Schiff base ligand sodium (6S)-7-((Z)-2-(methoxyimino)-2-(2-((Z)-2-oxoindolin-3-ylideneamino)thiazol-4-yl)acetamido)-3-((2-methyl-6-oxido-5-oxo-2,5-dihydro-1,2,4-triazin-3-ylthio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate (ISCR) derived from the condensation reaction of  ceftriaxone sodium (CR) with 1H-indole-2,3-dione (isatin, Is). The synthesized AuNPs were characterized by UV- visible spectroscopy, FTIR spectroscopy, X-ray diffraction (XRD), scanning electron microscope (SEM), and atomic force microscope (AFM).

Ceftriaxone; Isatin; Schiff base; AuNPs; surface plasmon bands

[ View HTML Full Text]