Abstract

Phanjoubam Pengkiliya Devi and Rajkumari Lonibala

DOI : http://dx.doi.org/10.13005/ojc/330331

A new Schiff base (R,E)-2-(dimethylamino)-3-(4-hydroxyphenyl)-N,2,3-trimethyl-N'-(1-p-tolylethylidene) butanehydrazide, Tmbh and Mn(II), Ni(II), Co(II), Cu(II) and Zn(II) complexes were synthesized and characterized on the basis of analytical, magnetic, cyclic voltammetric, conductometric, UV-Visible, TG/DTA, IR, NMR, EPR and mass spectral data. Tmbh acts as a uninegative/neutral bidentate ligand in all the complexes bonding through carbonyl oxygen and azomethine nitrogen. Half field signal observed in the ESR spectrum of Ni(II) complex is indicative of its dimeric nature and the trend in g-values suggest tetragonally distorted octahedral geometries for Co(II), Ni(II) and Cu(II) complexes.  All the complexes exhibit irreversible redox behavior. Morphology of Tmbh and the complexes have also been investigated through SEM and powder XRD data. Antimicrobial effects of the ligand and the complexes against the microbes Bacillus subtilis, Escherichia coli, Psuedomonas aeruginosa and Klebsiella pnuemonia are studied by diffusion method and the results show that the activities are increased upon complexation.

Schiff base; Transition metal complexes; Bidentate; Spectral studies; Irreversible redox behavior; Antimicrobial effects

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