Abstract

Azam Sargazi and Mostafa Heidari Majd

DOI : http://dx.doi.org/10.13005/ojc/330141

Toxic effects of mycotoxins are still an unresolved subject for health of humans and animals. Therefore, several methods has been created to determine and eliminate mycotoxins from foodstuffs, and also are developing. For instance, utilization of magnetic nanoparticles (MNPs) when are combined with different analytical tools is one of the developing methods which could be useful for extraction of mycotoxins. As in some methods, they were employed as newfound adsorbents in magnetic solid phase extraction approaches.In some other methods, MNPs were used for immobilization of antibodies to enhance the efficiency of the analytical tools such as square wave voltammetry. Or in another method, amine-functionalized MNPs were reacted with ochratoxin A (OTA) to enhance performance of chemiluminescence immunoassay. Results of all methods were showed that utilizing of MNPs could reduce cost, easy preparation, and increase the stability, speed, sensitivity, precision and reproducibility. So, these new methods have elicited great hopes to be suitable alternative for older methods.

Ochratoxin A; Extraction; MagneticSolid Phase Extraction; Aptamer-Targeted Magnetic Nanospheres; Chemiluminescence Immunoassay

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