ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
     FacebookTwitterLinkedinMendeley

Abstract

Construction and Performance Characterization of Ion Selective Electrodes for Potentiometric Determination of Citapolarm Hydrobromide in Biological Fluids

Amani S . Alturiqi1,2, Samar O. Aljazzar1,2,  Reda A. Ammar1,2 and Nuwair khalaf3

DOI : http://dx.doi.org/10.13005/ojc/330138


Abstract:

A coated-wire ion selective electrode based on ion-pair complex of citapolarm‎hydrobromide (CT)with sodium ‎tetraphenyl borate as electroactive material in the presence of dioctylphthalate (DOP)‎ as the plasticizing solvent mediatorwas prepared. The electrode displays Nernstian response of 56.83  mV/decade over the concentration range of  1.0×10-6 to 1.0×10-2mol/Lat 25 °C. The influence of membrane composition,  pH of the ‎test solutionand foreign ions on the electrode wereinvestigated.‎ The electrode was successfully applied to determination of the drug in pure form, urine and serum‎by standard addition potentiometry.

Keywords:

Citapolarm‎hydrobromide‎(CT); Ion selective electrodes; potentiometry

[ View HTML Full Text]

Back to TOC